Emphasize an Effective Bowel Regimen for Opioid-Induced Constipation

Naldemedine (Symproic, sim-PROH-ik) will be another option to treat adults with opioid-induced constipation.

It's a once-daily oral opioid antagonist similar to naloxegol (Movantik) or oral methylnaltrexone (Relistor). They all block opioid binding in the gut to increase GI motility...without affecting analgesia.

Lubiprostone (Amitiza) is another option for opioid-induced constipation. It increases fluid in the gut to stimulate GI motility.

Get unlimited access through an Enterprise license

Hospital Pharmacist's Letter includes:

  • 12 issues every year, with brief articles about new meds and hot topics
  • 300+ CE courses, including the popular CE-in-the-Letter
  • Quick reference drug comparison charts
  • Access to the entire archive

Already a subscriber? Log in

Not sold to individuals