Don't Rely on Anti-Xa Levels to Verify LMWH Efficacy or Safety
We're getting questions about how to dose low-molecular-weight heparin (LMWH) for venous thromboembolism in obesity and renal impairment.
Dosing a LMWH (enoxaparin, etc) can be tricky in these cases. Usual doses may not be enough for obese patients...or they may accumulate and be too much for patients with renal impairment.
Obesity. For acute venous thromboembolism (VTE) treatment, dose LMWH based on ACTUAL body weight...even in patients over 150 kg.