Consider Loperamide Overdose in Patients With Unexplained Cardiac Toxicity

July 2016

Please see the January 2018 FDA notice concerning new packaging for loperamide designed to limit abuse.

Abuse of OTC loperamide (Imodium A-D, etc) is skyrocketing...and is being linked to serious arrhythmias and deaths.

Loperamide went OTC in the 1980s...since its abuse potential was thought to be very low.

Fast-forward to 2016 and loperamide has earned the nickname "poor man's methadone"...because high doses can lead to opioid-like effects.

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