Put IV Metoclopramide Infusions in Perspective

September 2026

New evidence may change the way you see IV metoclopramide given in the emergency department (ED).

We’re used to seeing low-dose metoclopramide boluses of 5 to 10 mg given as a 2 min IV push for ED patients with headaches, nausea, and vomiting.

Conversely, higher doses ABOVE 10 mg are usually given as a 15 min IV piggyback (IVPB) bolus...to decrease extrapyramidal side effects (EPS) such as akathisia, dystonia, etc.


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