Manage Meds in Patients With Augmented Renal Clearance
Up to two-thirds of ICU patients may have augmented renal clearance (ARC).
These patients have a creatinine clearance above 130 mL/min...usually during their first week in the ICU. It seems partly due to increased cardiac output and renal perfusion.
The concern is that ARC may lead to inadequate blood levels of medication...due to faster clearance.
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