Limit Bleeding Risk in Patients Who Need an Anticoagulant Plus Antiplatelets

April 2017

Debate continues about how to manage patients on an anticoagulant (warfarin, etc) who also need antiplatelets (aspirin, etc).

Many patients end up on "triple antithrombotic therapy"...such as warfarin for atrial fib PLUS clopidogrel and aspirin after a stent.

But bleeding risk is high. One in 50 patients will have a serious bleed in the first month of triple therapy...and 1 in 8 in the first year.

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Table of Contents

Infectious Diseases Be Prepared to Treat Multidrug-Resistant "ESBL" and "CRE" Infections
Surgery Help Optimize Peri-Op Antifibrinolytic Use to Reduce Blood Transfusions
Nephrology Lean Toward Trying Urea Before "Vaptans" for Hyponatremia
Heart Failure Focus on BP Control in Heart Failure Patients With Preserved Ejection Fraction
Fall Risk Be Sure Your Facility Uses a Fall-Risk Medication Assessment
New Drugs Don't Expect the Constipation Med Plecanatide (Trulance) to Be on Your Formulary
Neurology & Pain Ask Patients on Pramipexole or Ropinirole About Worsening Restless Legs Syndrome
Antithrombotics Limit Bleeding Risk in Patients Who Need an Anticoagulant Plus Antiplatelets
Constipation Help Parents With Concerns About Miralax and Neuropsych Effects in Children
Topicals Help Prescribers Choose Between Different Topical Dosage Forms
Neuromuscular Start With Baclofen or Gabapentin for Persistent Hiccups
Hepatitis C Put Warnings About Liver Damage With Hep C Meds Into Perspective