Don't Expect the Constipation Med Plecanatide (Trulance) to Be on Your Formulary

Plecanatide (Trulance, TROO-lans) will be promoted for managing chronic constipation in adults.

Think of it as similar to linaclotide (Linzess) and lubiprostone (Amitiza). All of these meds increase fluid secretion in the intestines to help speed up GI transit.

They lead to about one or two more bowel movements per week in patients with chronic constipation...but cost about $12/day.

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