Save Icatibant for Airway Problems Due to ACE Inhibitor Angioedema
You'll see more interest in using icatibant (Firazyr, FEAR-ah-zear) for ACE inhibitor-associated angioedema.
This subcutaneous bradykinin receptor antagonist is only FDA approved for hereditary angioedema.
But new evidence suggests it's also effective for angioedema due to ACEIs. In fact, patients with ACEI-associated angioedema who receive icatibant 30 mg seem to have complete symptom resolution 19 hours sooner...when compared to usual care.