Expect Trikafta to Be a Game Changer for Cystic Fibrosis

Trikafta (try-KAF-tuh, elexacaftor/tezacaftor/ivacaftor) will be a game changer for treating cystic fibrosis (CF).

It targets a gene mutation found in nearly 90% of CF patients.

CF transmembrane conductance regulator (CFTR) modulators already on the market...Kalydeco, Orkambi, and Symdeko...target genetic mutations found in fewer than 50% of patients.

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