Continue to Avoid Quinolones When Possible

September 2018

Stronger warnings will lead to more concerns about quinolone risks.

Quinolone labels already caution about hypo- and hyperglycemia...and certain CNS effects, such as agitation, nervousness, or confusion.

Now FDA will require warnings of hypoglycemic coma...especially in the elderly, renal impairment, or in combo with insulin or a sulfonylurea.

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Table of Contents

Antibiotics Don't Expect the New Antibiotic Plazomicin to Be Added to Formulary
Thrombolytics Weigh Thrombolytic Pros and Cons for Submassive Pulmonary Embolism
Bites & Stings Know the Difference Between CroFab and the New Snakebite Antivenom Anavip
Recalls The Valsartan Recall May Shake Up ARB Use at Your Hospital
Antibiotics Continue to Avoid Quinolones When Possible
New Drugs Stick With Clonidine When Using a Non-Opioid to Manage Acute Opioid Withdrawal
Diabetes Don't Jump to Newer Diabetes Meds for Renal Protection Yet
New Drugs Watch for Epidiolex, a New Rx Cannabinoid
Gout Consider Holding Febuxostat in Patients Admitted with CV Disease
New Drugs Hold the Low-Dose Vaginal Estrogen Imvexxy During Hospitalization