Stick With Clonidine When Using a Non-Opioid to Manage Acute Opioid Withdrawal
Lofexidine (Lucemyra, loo-seh-MEER-uh) will be a new NON-opioid to help manage opioid withdrawal symptoms.
Think of lofexidine as similar to clonidine.
Both are alpha-2 agonists. Clonidine has been used off-label for years to treat withdrawal symptoms...such as agitation, muscle aches, nausea, and diarrhea.