Move to the CKD-EPIcr Creatinine Equation for Kidney Dosing
October 2026
New guidance emphasizes moving away from the Cockcroft-Gault equation to estimate kidney function for drug dosing in adults.
The National Kidney Foundation and other organizations advocate using the 2021 CKD-EPI creatinine (CKD-EPIcr) equation instead...it’s more accurate at calculating an estimated glomerular filtration rate (eGFR).
Unlike Cockcroft-Gault, CKD-EPIcr was validated in a large, diverse population with stable kidney function using standardized creatinine labs.
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