Review Data Behind Expanded Thrombolytic Timing for Strokes
October 2025
Recent evidence is stirring discussion on whether to reconsider time limits for using thrombolytics (alteplase, etc) after an ischemic stroke.
We know thrombolytics are typically given within 4.5 hours after stroke symptoms start. But there’s interest in using these past this mark for some cases.
For example, this deadline can limit options in cases where stroke onset is unclear, such as patients who awake with symptoms, etc.
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