Be Familiar With Aprocitentan for Resistant Hypertension

December 2024

Aprocitentan (Tryvio), a new oral med for resistant hypertension in adults, will pop up on some home med lists.

It’s the first dual endothelin antagonist approved for resistant hypertension. Endothelin is a vasoconstrictor and aldosterone mediator.

Think of it as similar to other endothelin receptor antagonists, such as bosentan...but these are for pulmonary arterial hypertension.

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