Sort Through Specifics of Penicillin Allergies

May 2023

Approximately 80% of IgE-mediated penicillin allergies are lost over 10 years.

And mounting data suggest that cross-reactivity is based more on sharing an R1 side chain...rather than the beta-lactam ring or the cephalosporin generation.

For example, amoxicillin shares a SIMILAR R1 side chain with cephalexin. And aztreonam, ceftazidime, and cefiderocol share the SAME R1 side chain.

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