Consider Cefazolin as a First-Line Option for MSSA Bacteremia

You'll see cefazolin preferred over nafcillin in some methicillin-sensitive Staph aureus (MSSA) bacteremia patients.

We know to switch MSSA bacteremia patients from vancomycin to a beta-lactam for more effective coverage...including in patients with a rash or other mild reactions to penicillin.

But which beta-lactam should you choose?

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