Think of Kloxxado as a Higher-Dose Naloxone Nasal Spray

Kloxxado, a new naloxone nasal spray, will raise questions about which product to use in patients taking opioids.

Think of Kloxxado as having twice as much naloxone per dose as Narcan nasal spray. Kloxxado contains 8 mg naloxone per spray...Narcan has 4 mg per spray.

There's some buzz that higher naloxone doses may be needed, since overdoses from "ultra-potent" fentanyl-like compounds are on the rise.