Guide Med Adjustments in Liver Impairment
You'll be asked about med adjustments in patients with liver impairment...since package inserts often lack clear guidance.
Liver enzymes (ALT, AST) are a marker of liver injury...not function. In fact, ALT and AST may be normal in advanced cirrhosis.
Continue to use elevated liver enzymes to detect drug-induced liver injury...and stop possible culprits (acetaminophen, statins, kava, etc).