Guide Med Adjustments in Liver Impairment

May 2021

You'll be asked about med adjustments in patients with liver impairment...since package inserts often lack clear guidance.

Liver enzymes (ALT, AST) are a marker of liver injury...not function. In fact, ALT and AST may be normal in advanced cirrhosis.

Continue to use elevated liver enzymes to detect drug-induced liver injury...and stop possible culprits (acetaminophen, statins, kava, etc).

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Table of Contents

COVID-19 Address Concerns About Thrombosis With COVID-19 Vaccines
Pumps Safely Transition Patients Using an Insulin Pump
COVID-19 Implement Strategies to Prevent COVID-19 Vaccine Errors
Medication Errors Help Combat Errors With Labor and Delivery Meds
Liver Disease Guide Med Adjustments in Liver Impairment
Pediatrics Look for Opportunities to Improve Pediatric Antimicrobial Use
Hormone Therapy Manage Transitions of Care With Transgender Therapies
Practice Take a "Buyer Beware" Approach With Preliminary Data
Hypertension Don't Consider a Specific Thiazide the "Clear Winner" for Hypertension
Topicals Put Systemic Effects of Topical Steroids in Perspective