Expect Less Focus on Psychiatric Effects With Varenicline

February 2017

Boxed warnings about psychiatric events will be REMOVED from varenicline (Chantix) and bupropion labeling for smoking cessation.

These warnings about mood changes, agitation, nightmares, and other psychiatric risks were originally added based on case reports.

Now a large trial suggests that these meds do NOT increase psychiatric side effects in patients quitting smoking.

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Table of Contents

Antipsychotics Know When to Choose an Antipsychotic or Benzo for Acute Agitation
Surgery Consider Stopping ACEIs and ARBs Preoperatively in Some Patients
Infectious Diseases Don't Yet Rely on Bezlotoxumab to Lower Risk of Recurrent C. diff Diarrhea
COPD Expect Fewer Inhaled Steroids to Be Used in Chronic COPD Patients
Anesthesiology Help Parents Understand the Warning About General Anesthesia Use in Kids
Muscle Relaxants Limit Use of Muscle Relaxants in Hospitalized Patients
Hypotension Check for Medication Causes of Orthostatic Hypotension
Smoking Cessation Expect Less Focus on Psychiatric Effects With Varenicline
NSAIDs Feel Comfortable Using NSAIDs After Most Orthopedic Surgeries
Renal & Urology Consider Tamsulosin for Kidney Stones About 5 mm to 10 mm in Size
Interactions Watch for Statin Interactions With Dabigatran