Don't Use Serum Creatinine Cutoffs Anymore For Metformin

June 2016

Metformin will be used in more diabetes patients with kidney disease...as FDA labeling catches up with the evidence.

We're used to avoiding metformin if serum creatinine is over 1.5 mg/dL for men or over 1.4 mg/dL in women...due to fear of lactic acidosis.

But lactic acidosis is EXTREMELY rare...even in kidney disease.

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